Review
doi: 10.1038/10039.
Regulation of the APC and the exit from mitosis
Affiliations
- PMID: 10559897
- DOI: 10.1038/10039
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Review
Regulation of the APC and the exit from mitosis
Nat Cell Biol.
1999 Jun.
Abstract
The events of late mitosis, from sister-chromatid separation to cytokinesis, are governed by the anaphase-promoting complex (APC), a multisubunit assembly that triggers the ubiquitin-dependent proteloysis of key regulatory proteins. An intricate regulatory network governs APC activity and helps to ensure that late mitotic events are properly timed and coordinated.
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