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Comparative Study
. 1999 Nov 18;9(22):R842-4.
doi: 10.1016/s0960-9822(00)80041-x.

Molecular evolution: aminoacyl-tRNA synthetases on the loose

A M Weiner  1
Affiliations
Free article
Comparative Study

Molecular evolution: aminoacyl-tRNA synthetases on the loose

A M Weiner. Curr Biol. .
Free article

Abstract

Modified versions - paralogs - of the catalytic domain of at least three different aminoacyl-tRNA synthetases have been found to serve catalytic or regulatory roles in other reactions. These findings suggest that the first modern tRNA-synthetases could have been derived from amino-acid biosynthetic enzymes.

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