doi: 10.1101/sqb.1974.039.01.076.
Analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells
- PMID: 1057486
- DOI: 10.1101/sqb.1974.039.01.076
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Analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells
Cold Spring Harb Symp Quant Biol.
1975.
Abstract
The presence of multiple copies of a portion of the viral genome was demonstrated in Ad7-transformed cells by a new method based on the kinetic analysis of labeled viral DNA reassociation in the presence of unlabeled transformed cell DNA. DNA-DNA homology measurement utilizing defined DNA fragments (restriction endonuclease digests) as labeled probes supported the above conclusion.
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