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. 1975:39 Pt 1:633-6.
doi: 10.1101/sqb.1974.039.01.076.

Analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells

K Fujinaga, K Sekikawa, H Yamazaki, M Green

Analysis of multiple viral genome fragments in adenovirus 7-transformed hamster cells

K Fujinaga et al. Cold Spring Harb Symp Quant Biol. 1975.

Abstract

The presence of multiple copies of a portion of the viral genome was demonstrated in Ad7-transformed cells by a new method based on the kinetic analysis of labeled viral DNA reassociation in the presence of unlabeled transformed cell DNA. DNA-DNA homology measurement utilizing defined DNA fragments (restriction endonuclease digests) as labeled probes supported the above conclusion.

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