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. 1999 Oct;65(7):595-9.
doi: 10.1055/s-1999-14030.

Aggregation inhibitory activity of minor acetophenones from Paeonia species

H C Lin  1 , H Y Ding, F N Ko, C M Teng, Y C Wu
Affiliations

Aggregation inhibitory activity of minor acetophenones from Paeonia species

H C Lin et al. Planta Med. 1999 Oct.

Abstract

Two minor acetophenones, 2,5-dihydroxy-4-methoxy-acetophenone (2) and 2,5-dihydroxy-4-methylacetophenone (7) from Paeonia species were found to selectively inhibit the aggregation of rabbit platelets induced by arachidonic acid. They were more potent than the major compound, paeonol (1), and 7 also inhibited the formation of TXA2 and PGD2 from arachidonic acid.

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