Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Comment
. 1999 Oct;114(4):597-9.
doi: 10.1085/jgp.114.4.597.

Test of Poisson-Nernst-Planck theory in ion channels

Comment

Test of Poisson-Nernst-Planck theory in ion channels

B Corry et al. J Gen Physiol. 1999 Oct.
No abstract available

PubMed Disclaimer

Figures

Figure 1
Figure 1
Cross section of the cylindrical channel used in the comparisons (top). The length of the channel is 35 Å, including the rounded corners, which have a radius of 5 Å. The dielectric constants are 80 in the channel and 2 in the protein. An electric field of E = 107 V/m is applied as indicated by the arrow. The dotted lines show the layers used in the concentration plot below. (A) Concentration profiles of Na+ ions in a 4-Å radius channel as predicted from PNP theory (•) and BD simulations (histograms). The shaded areas indicate the reservoir values. (B) Conductance of ions, normalized by the cross-sectional area, are plotted against the channel radius. The results obtained from the BD simulations (•, Na+; ○, Cl) are fitted by the dotted lines. The PNP results are shown by the solid lines.

Comment on

  • Modeling of ion channels.
    Levitt DG. Levitt DG. J Gen Physiol. 1999 Jun;113(6):789-94. doi: 10.1085/jgp.113.6.789. J Gen Physiol. 1999. PMID: 10352030 Free PMC article. Review. No abstract available.

Similar articles

Cited by

References

    1. Chung S.H., Hoyles M., Allen T.W., Kuyucak S. Study of ionic currents across a model membrane channel using Brownian dynamics. Biophys. J. 1998;75:793–809. - PMC - PubMed
    1. Chung S.H., Allen T.W., Hoyles M., Kuyucak S. Permeation of ions across the potassium channelBrownian dynamics studies. Biophys. J. 1999;In press - PMC - PubMed
    1. Cooper K.E., Jakobsson E., Wolynes P. The theory of ion transport through membrane channels. Prog. Biophys. Mol. Biol. 1985;46:51–96. - PubMed
    1. Eisenberg R.S. Computing the field in proteins and channels. J. Membr. Biol. 1996;150:1–25. - PubMed
    1. Hoyles M., Kuyucak S., Chung S.H. Computer simulation of ion conductance in membrane channels. Phys. Rev. E. 1998;58:3654–3661.