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Editorial
. 1999 Dec;65(6):1489-92.
doi: 10.1086/302668.

The size distribution of homozygous segments in the human genome

A G Clark
Editorial

The size distribution of homozygous segments in the human genome

A G Clark. Am J Hum Genet. 1999 Dec.
No abstract available

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Figures

Figure 1
Figure 1
A, Decline in size of unrecombined segments with increasing numbers of recombination events. The solid line is from the theoretical prediction (eq. 1), and the dots are from 1000 replicates of dropping recombination events on a unit line (length 100 cM). B, Distribution of lengths of unrecombined segments for 10 recombination events (hatched bars) and for 50 recombination events (solid bars).
See this image and copyright information in PMC

Comment on

References

    1. Beerli P, Felsenstein J (1999) Maximum-likelihood estimation of migration rates and effective population numbers in two populations using a coalescent approach. Genetics 152:763–773 - PMC - PubMed
    1. Bertorelle G, Slatkin M (1995) The number of segregating sites in expanding human populations, with implications for estimates of demographic parameters. Mol Biol Evol 12:887–892 - PubMed
    1. Broman KW, Weber JL (1999) Long homozygous chromosomal segments in the CEPH families. Am J Hum Genet 65:1493-1500 (in this issue) - PMC - PubMed
    1. Clark AG, Weiss KM, Nickerson DA, Taylor SL, Buchanan A, Stengård J, Salomaa V, et al (1998) Haplotype structure and population genetic inferences from nucleotide-sequence variation in human lipoprotein lipase. Am J Hum Genet 63:595–612 - PMC - PubMed
    1. Donnelly PJ, Wiuf C (1999) Shared chromosomal segments and genome-wide association mapping. Am J Hum Genet 65:A83

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