Paths of glorious proteases
- PMID: 10581013
- DOI: 10.1038/70472
Paths of glorious proteases
Comment on
-
Loss-of-function mutations in the cathepsin C gene result in periodontal disease and palmoplantar keratosis.Nat Genet. 1999 Dec;23(4):421-4. doi: 10.1038/70525. Nat Genet. 1999. PMID: 10581027
Similar articles
-
Papillon-Lefèvre syndrome: correlating the molecular, cellular, and clinical consequences of cathepsin C/dipeptidyl peptidase I deficiency in humans.J Immunol. 2004 Dec 15;173(12):7277-81. doi: 10.4049/jimmunol.173.12.7277. J Immunol. 2004. PMID: 15585850
-
Loss-of-function mutations in cathepsin C in two families with Papillon-Lefèvre syndrome are associated with deficiency of serine proteinases in PMNs.Hum Mutat. 2004 May;23(5):524. doi: 10.1002/humu.9243. Hum Mutat. 2004. PMID: 15108292
-
A family with Papillon-Lefevre syndrome reveals a requirement for cathepsin C in granzyme B activation and NK cell cytolytic activity.Blood. 2006 May 1;107(9):3665-8. doi: 10.1182/blood-2005-03-1140. Epub 2006 Jan 12. Blood. 2006. PMID: 16410452
-
Papillon-Lefevre syndrome: clinical presentation and a brief review.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009 Jul;108(1):e1-7. doi: 10.1016/j.tripleo.2009.03.016. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2009. PMID: 19540439 Review.
-
Papillon-Lefèvre syndrome with albinism: a review of the literature and report of 2 brothers.Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005 Dec;100(6):709-16. doi: 10.1016/j.tripleo.2004.08.030. Oral Surg Oral Med Oral Pathol Oral Radiol Endod. 2005. PMID: 16301152 Review.
Cited by
-
Cytokine production by leukocytes of Papillon-Lefèvre syndrome patients in whole blood cultures.Clin Oral Investig. 2012 Apr;16(2):591-7. doi: 10.1007/s00784-011-0532-0. Epub 2011 Mar 5. Clin Oral Investig. 2012. PMID: 21380503
-
Lysosomal protease expression in mature enamel.Cells Tissues Organs. 2009;189(1-4):111-4. doi: 10.1159/000151431. Epub 2008 Aug 15. Cells Tissues Organs. 2009. PMID: 18703868 Free PMC article.
-
Safety, tolerability, pharmacokinetics and pharmacodynamics of HSK31858, a novel oral dipeptidyl peptidase-1 inhibitor, in healthy volunteers: An integrated phase 1, randomized, double-blind, placebo-controlled, single- and multiple-ascending dose study.Br J Clin Pharmacol. 2025 Aug;91(8):2262-2272. doi: 10.1002/bcp.70027. Epub 2025 Apr 2. Br J Clin Pharmacol. 2025. PMID: 40170587 Free PMC article. Clinical Trial.
-
Residual active granzyme B in cathepsin C-null lymphocytes is sufficient for perforin-dependent target cell apoptosis.J Cell Biol. 2007 Feb 12;176(4):425-33. doi: 10.1083/jcb.200609077. Epub 2007 Feb 5. J Cell Biol. 2007. PMID: 17283185 Free PMC article.
-
A Phase 2 randomised study to establish efficacy, safety and dosing of a novel oral cathepsin C inhibitor, BI 1291583, in adults with bronchiectasis: Airleaf.ERJ Open Res. 2023 Jun 26;9(3):00633-2022. doi: 10.1183/23120541.00633-2022. eCollection 2023 May. ERJ Open Res. 2023. PMID: 37465817 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources
Research Materials