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Review
. 1999 Dec 4;319(7223):1480-5.
doi: 10.1136/bmj.319.7223.1480.

Management of Crohn's disease

Affiliations
Review

Management of Crohn's disease

D S Rampton. BMJ. .
No abstract available

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Figures

Figure 1
Figure 1
Aetiopathogenesis of Crohn's disease. Genetic and environmental factors activate mucosal T lymphocytes causing cytokine driven inflammation; increased epithelial permeability and granulomatous vasculitis, leading to focal intestinal microinfarction, may also contribute to the inflammatory process
Figure 2
Figure 2
Superficial aphthoid erosions in sigmoid colon in patient with ileocolonic Crohn's disease. Subtle lesions such as these are more readily seen at ileocolonoscopy than on barium enema

References

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    1. Cosnes J, Carbonnel F, Beaugerie L, Le Quintrec Y, Gendre JP. Effects of cigarette smoking on the long-term course of Crohn's disease. Gastroenterology. 1996;110:424–431. - PubMed
    1. Hanauer SB, Meyers S. Management of Crohn's disease in adults. Am J Gastroenterol. 1997;92:559–566. - PubMed
    1. Hanauer SB. Inflammatory bowel disease. N Engl J Med. 1996;334:841–848. - PubMed
    1. Hodgson HJF. Laboratory markers of inflammatory bowel disease. In: Allan RN, Rhodes JM, Hanauer SB, Keighley MF, Alexander-Williams J, Fazio VW, editors. Inflammatory bowel diseases. New York: Churchill Livingstone; 1997. pp. 329–334.

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