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. 1999 Oct;44(4):553-5.
doi: 10.1093/jac/44.4.553.

In-vitro susceptibility of Aspergillus spp. isolates to amphotericin B and itraconazole

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In-vitro susceptibility of Aspergillus spp. isolates to amphotericin B and itraconazole

E Dannaoui et al. J Antimicrob Chemother. 1999 Oct.

Abstract

The MICs of amphotericin B and itraconazole for 230 isolates of Aspergillus spp., comprising 156 Aspergillus fumigatus, 20 Aspergillus terreus, 22 Aspergillus flavus, 17 Aspergillus nidulans and 15 Aspergillus niger, were determined by a broth microdilution method with RPMI 1640 medium. No isolate was detected with an MIC of amphotericin B >2 mg/L. Itraconazole MICs >16 mg/L were detected for four Aspergillus fumigatus and one Aspergillus nidulans isolates.

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