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Comment
. 1999 Dec 7;96(25):14180-2.
doi: 10.1073/pnas.96.25.14180.

Escapees on the X chromosome

C M Disteche
Comment

Escapees on the X chromosome

C M Disteche. Proc Natl Acad Sci U S A. .
No abstract available

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Figures

Figure 1
Figure 1
Dosage of genes on the sex chromosomes in relation to biallelically expressed autosomal genes (blue). In females, genes on the X can either be subject to inactivation on the inactive X (white) and up-regulated on the active X (red), or they can escape (pink). In males, genes on the X are either up-regulated (red) or not (pink), and genes on the Y either are lost, are differentiated to acquire a male-specific function (green), or persist as functionally equivalent Y partners in X/Y gene pairs (pink).
Figure 2
Figure 2
Ideograms of the human and mouse X chromosomes indicating the position of the centromere (crosshatched), of the XCR (X-conserved region, filled), of the XAR (X-added region, unfilled), and of the pseudoautosomal region (PAR), dotted (8). (Left) The approximate position of evolutionary strata, 1, 2, 3, and 4, defined by Lahn and Page (9). The position of escapees is indicated (Right) with the X/Y genes indicated in red (genes with functional and nonfunctional Y partners included) and the X-only escapees in blue.
See this image and copyright information in PMC

Comment on

References

    1. Lyon M. Nature (London) 1961;190:372–373. - PubMed
    1. Disteche C M. Trends Genet. 1995;11:17–22. - PubMed
    1. Carrel L, Cottle A A, Goglin K C, Willard H F. Proc Natl Acad Sci USA. 1999;96:14440–14444. - PMC - PubMed
    1. Ohno S. Sex Chromosomes and Sex Linked Genes. Berlin: Springer; 1967.
    1. Rice W R. BioScience. 1996;46:331–343.

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