Clinical Trial
Methotrexate and leflunomide combination therapy for patients with active rheumatoid arthritis
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- PMID: 10589360
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Clinical Trial
Methotrexate and leflunomide combination therapy for patients with active rheumatoid arthritis
Clin Exp Rheumatol.
1999 Nov-Dec.
Abstract
An open-label, one-year study was conducted to evaluate the safety and clinical response to leflunomide and methotrexate combination therapy for rheumatoid arthritis. Study results revealed tolerable safety, no significant pharmacokinetic interactions between methotrexate and leflunomide, and suggested improved clinical response with combination therapy.
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