Electron microscopy of defined lengths of chromatin
- PMID: 1059115
- PMCID: PMC432983
- DOI: 10.1073/pnas.72.9.3320
Electron microscopy of defined lengths of chromatin
Abstract
Defined lengths of chromatin were prepared by brief digestion with micrococcal nuclease and fractionation in a sucrose gradient. A length containing a given number of 200 base pair repeating units appeared as the same number of 100 A beads in the electron microscope. The distance between beads within a length was small, usually less than about 20 A.
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