Complex regional pain syndrome: becoming more or less complex?

Abstract

Complex regional pain syndrome (CRPS) is the newest name for the confusing conditions of reflex sympathetic dystrophy and causalgia. The epidemiology and the signs and symptoms of these conditions are discussed. Although much is only poorly understood about the aetiology of CRPS, the roles of neuropathic pain, prolonged inflammation and psychological factors are becoming clearer. Physical therapies remain the lynchpin of management but the roles of anti-inflammatory medication, sympathectomies and a team approach are emphasized.