Patients with stages III and IV endometriosis have a poorer outcome of in vitro fertilization-embryo transfer than patients with tubal infertility
- PMID: 10593389
- DOI: 10.1016/s0015-0282(99)00392-1
Patients with stages III and IV endometriosis have a poorer outcome of in vitro fertilization-embryo transfer than patients with tubal infertility
Abstract
Objective: To evaluate the outcome of IVF in patients with stages III and IV endometriosis.
Design: Retrospective study.
Setting: The Sara Racine IVF Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Israel.
Patient(s): Fifty-eight patients with stages III and IV endometriosis and 60 patients with tubal infertility.
Intervention(s): IVF-ET for all couples.
Main outcome measure(s): Fertilization, pregnancy, and birth rates.
Result(s): The comparison between patients with endometriosis and those with tubal infertility indicated that the former had a poor IVF outcome in terms of reduced fertilization rate (40% vs. 70%), reduced pregnancy rate per cycle (10.6% vs. 22.4%), and reduced birth rate per cycle (6.7% vs. 16.6%). The differences were statistically significant.
Conclusion(s): The results show an unfavorable outcome of IVF-ET in patients with endometriosis when compared with those who have tubal infertility.
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