[Aerobic-hemodynamic support of physical exertion in virtually healthy persons with different levels of cholesterol in the blood and in patients with stenocardia of effort]

Abstract

Oxygen transport and central hemodynamics were studied in 66 healthy males with different blood cholesterol levels and 24 patients with angina of effort under standard exercise test. Increased blood cholesterol was found to influence exercise energy maintenance in healthy people. Subnormal efficacy of oxygen transport system provokes intensification of cardiac activity. Oxygen-hemodynamic maintenance of exercise in healthy subjects with hypercholesterolemia is similar to that in patients with ischemic heart disease. This indicates the same pathophysiological processes in the above individuals.