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. 1999;106(9-10):925-9.
doi: 10.1007/s007020050212.

An overnight switch to ropinirole therapy in patients with Parkinson's disease. Short communication

M Canesi  1 , A Antonini, C B Mariani, S Tesei, A L Zecchinelli, M Barichella, G Pezzoli
Affiliations

An overnight switch to ropinirole therapy in patients with Parkinson's disease. Short communication

M Canesi et al. J Neural Transm (Vienna). 1999.

Abstract

Patients with Parkinson's disease (n = 68) switched from pergolide or bromocriptine to ropinirole overnight (dose equivalence ratios 1:6 and 10:6, respectively). The activities of daily living score for the Unified Parkinson's Disease Rating Scale (UPDRS) was significantly improved 4 weeks after the bromocriptine-ropinirole switch. All other UPDRS scores, including that for the side-effect component, were not significantly different after either switch. Overnight switching may be a safe therapeutic approach that may reduce hospitalisation and related socio-economic costs.

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