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. 1975 Oct;72(10):3898-901.
doi: 10.1073/pnas.72.10.3898.

Cell-free synthesis of human interferon

Cell-free synthesis of human interferon

S Pestka et al. Proc Natl Acad Sci U S A. 1975 Oct.

Abstract

With mRNA prepared from induced human fibroblasts biologically active human interferon was synthesized de novo in a cell-free extract from mouse cells. The identity of the antiviral activity as human interferon was demonstrated by its species and antigenic specificity.

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