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. 1999 Dec 3;38(23):3504-3506.
doi: 10.1002/(sici)1521-3773(19991203)38:23<3504::aid-anie3504>3.0.co;2-e.

The First Catalytic Asymmetric Nitro-Mannich-Type Reaction Promoted by a New Heterobimetallic Complex

Ki Yamada  1 , SJ Harwood, H Gröger, M Shibasaki
Affiliations

The First Catalytic Asymmetric Nitro-Mannich-Type Reaction Promoted by a New Heterobimetallic Complex

Ki Yamada et al. Angew Chem Int Ed Engl. .

Abstract

The best ratio is 1:1:3 for the components Yb, K, and binaphthol in the new heterobimetallic complex, which efficiently catalyzes an asymmetric nitro-Mannich-type reaction. The desired nitro-Mannich products 2 are obtained with up to 91 % ee starting from N-phosphinoyl imines 1.

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