Pathogenicity of Cryptococcus neoformans: virulence factors and immunological mechanisms
- PMID: 10602663
- DOI: 10.1016/s1286-4579(99)80025-2
Pathogenicity of Cryptococcus neoformans: virulence factors and immunological mechanisms
Abstract
Cryptococcus neoformans is the causative agent of cryptococcosis and cryptococcal meningitis, which are serious pathological conditions affecting up to 10% of patients with AIDS. Mechanisms of pathogenicity of C. neoformans and the host defenses against this fungus are reviewed, incorporating recent data and perspectives.
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