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Review
. 2000 Jan 1;59(1):35-41.
doi: 10.1016/s0006-2952(99)00298-1.

Redox regulation of signal transduction in mammalian cells

P Herrlich  1 , F D Böhmer
Affiliations
Review

Redox regulation of signal transduction in mammalian cells

P Herrlich et al. Biochem Pharmacol. .

Abstract

This mini-review addresses the mechanism of ultraviolet-light-induced activation of receptor tyrosine kinases. The experimental approach into this mechanism revealed the existence of redox regulation of signal transduction in mammalian cells. It is postulated that, in addition to responsiveness to oxidative attacks from outside, redox regulation of specific redox-sensitive proteins likely represents an important physiological mechanism.

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