Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
. 1999 Dec 17;463(3):285-8.
doi: 10.1016/s0014-5793(99)01632-4.

Histone- and chromatin-binding activity of template activating factor-I

K Matsumoto  1 , K Nagata, M Okuwaki, M Tsujimoto
Affiliations
Free article

Histone- and chromatin-binding activity of template activating factor-I

K Matsumoto et al. FEBS Lett. .
Free article

Abstract

Template activating factor-I (TAF-I) is a histone-binding chromatin remodeling factor. We recently found that TAF-I is capable of mediating decondensation of Xenopus sperm chromatin by releasing sperm-specific basic proteins. Here we present evidence that TAF-I preferentially binds to histone H3 among four core histones. Immunofluorescent staining revealed that TAF-I binds to the decondensed sperm chromatin, of which protein components predominantly consist of histones H3 and H4.

PubMed Disclaimer

Publication types

LinkOut - more resources