Review
doi: 10.1016/s0960-9822(00)80108-6.
B-cell commitment: Pax5 is the deciding factor
Affiliations
- PMID: 10607584
- DOI: 10.1016/s0960-9822(00)80108-6
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Review
B-cell commitment: Pax5 is the deciding factor
Curr Biol.
1999 Dec.
Free article
Abstract
Recent studies have identified the transcription factor Pax5 as a critical determinant of commitment to the B-lymphocyte pathway. Surprisingly, Pax5 appears to achieve this primarily through suppressing alternative haematopoietic lineage fates.
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