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Review
. 1999 Dec;9(24):R933-5.
doi: 10.1016/s0960-9822(00)80108-6.

B-cell commitment: Pax5 is the deciding factor

T Enver  1
Affiliations
Free article
Review

B-cell commitment: Pax5 is the deciding factor

T Enver. Curr Biol. 1999 Dec.
Free article

Abstract

Recent studies have identified the transcription factor Pax5 as a critical determinant of commitment to the B-lymphocyte pathway. Surprisingly, Pax5 appears to achieve this primarily through suppressing alternative haematopoietic lineage fates.

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