Review
doi: 10.1016/s0959-440x(99)00027-5.
Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase
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- PMID: 10607667
- DOI: 10.1016/s0959-440x(99)00027-5
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Review
Structure and electron transfer mechanism of pyruvate:ferredoxin oxidoreductase
Curr Opin Struct Biol.
1999 Dec.
Abstract
The first crystal structure of pyruvate:ferredoxin oxidoreductase to be determined has provided significant new information on its structural organization and redox chemistry. Spectroscopic analyses of a radical reaction intermediate have shed more light on its thiamin-based mechanism of catalysis. Different approaches have been used to study the interaction between the enzyme and ferredoxin, its redox partner.
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