Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1999 Dec;9(6):754-9.
doi: 10.1016/s0959-440x(99)00040-8.

Signal sequence recognition and protein targeting

R M Stroud  1 , P Walter
Affiliations
Review

Signal sequence recognition and protein targeting

R M Stroud et al. Curr Opin Struct Biol. 1999 Dec.

Abstract

Intracellular traffic is often controlled not by highways, but by handshakes and partner introductions within a cellular network. Recently determined structures suggest how signal sequences are recognized and how the GTP affinities of the signal recognition particle and its receptor are coupled to the targeting of ribosomes to translocational membrane pores. The structure of signal peptidase suggests how it releases functional proteins.

PubMed Disclaimer

Publication types

LinkOut - more resources