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. 1999 Dec;38(12):1913-5.
doi: 10.1016/s0028-3908(99)00109-4.

MTSEA potentiates 5-HT3 receptors containing the nicotinic alpha4 subunit

S Kriegler  1 , S Sudweeks, J L Yakel
Affiliations

MTSEA potentiates 5-HT3 receptors containing the nicotinic alpha4 subunit

S Kriegler et al. Neuropharmacology. 1999 Dec.

Abstract

In order to study the subunit composition of 5-HT3 receptors (5-HT3R), we report that (2-aminoethyl)methanethiosulfonate (MTSEA) can enhance the function of both nicotinic ACh receptors (nAChRs) comprised of alpha4/beta2 subunits, and heteromeric channels assembled from serotonin 5-HT3R and alpha4 nAChR subunits. MTSEA has no effect on homomeric 5-HT3 receptor channels.

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