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Review
. 1999 Nov-Dec;17(6):741-4.

Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema

F Cantini  1 , C Salvarani, I Olivieri
Affiliations
  • PMID: 10609077
Review

Paraneoplastic remitting seronegative symmetrical synovitis with pitting edema

F Cantini et al. Clin Exp Rheumatol. 1999 Nov-Dec.

Abstract

Remitting seronegative symmetrical synovitis with pitting edema (RS3PE) is a syndrome that may be associated with many conditions, including malignancy. Three further cases of paraneoplastic RS3PE are described and the literature is reviewed. Paraneoplastic RS3PE is more frequently associated with solid tumors, in particular adenocarcinoma. The two clinical characteristics suggestive of paraneoplastic RS3PE are systemic sign/symptoms and the poor response to corticosteroid therapy.

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