Roles of lipoarabinomannan in the pathogenesis of tuberculosis
- PMID: 10611748
- DOI: 10.1016/s1286-4579(99)80072-0
Roles of lipoarabinomannan in the pathogenesis of tuberculosis
Abstract
Tuberculosis is a worldwide public health threat caused by Mycobacterium tuberculosis. All mycobacteria express a unique cell envelope glycolipid, lipoarabinomannan, which can be released at sites of infection. Lipoarabinomannan is a potential virulence factor which can bind to leukocytes and modulate immune responses. Here, we provide an overview of the interactions of mycobacteria and lipoarabinomannan with immune cells.
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