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. 1999 Oct:53 Suppl 2:S89-90.

[Intermittent assisted ventilation in neuromuscular diseases: course and quality of life]

[Article in German]
H Hein  1 , B Schucher, H Magnussen
Affiliations
  • PMID: 10613050

[Intermittent assisted ventilation in neuromuscular diseases: course and quality of life]

[Article in German]
H Hein et al. Pneumologie. 1999 Oct.

Abstract

Intermittent non-invasive home ventilation is expected to improve the quality of life, but progression of underlying neuromuscular diseases may lead to a deterioration. We observed after 82-1085 days of such home mechanical ventilation (7 patients with muscular dystrophy (age [mean/std.) 33 +/- 15 years), 8 patients with amyotrophic lateral sclerosis (ALS. age 60 +/- 8 years) a nonsignificant decrease of vital capacity (1.6 +/- 0.4 rp. 1.2 +/- 0.4 l) and an improvement of hypercapnia (49.3 +/- 8.5 rp. 43 +/- 18.5 mmHg). Quality of life (SF-36, Medical Outcomes Trust, Boston, USA) increased significantly only for mental health in patients with ALS (55 +/- 13 rp. 64 +/- 17%). Despite progression of the underlying disease the quality of life remained stable under home mechanical ventilation and mental health improved.

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