doi: 10.1016/S0140-6736(99)05582-8.
Hypocretin (orexin) deficiency in human narcolepsy
- PMID: 10615891
- DOI: 10.1016/S0140-6736(99)05582-8
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Hypocretin (orexin) deficiency in human narcolepsy
Lancet.
.
Free article
Abstract
Alterations in the hypocretin receptor 2 and preprohypocretin genes produce narcolepsy in animal models. Hypocretin was undetectable in seven out of nine people with narcolepsy, indicating abnormal hypocretin transmission.
Comment in
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Hypocretin (orexin) pathway to sleep.Lancet. 2000 Jan 1;355(9197):6. doi: 10.1016/S0140-6736(99)90468-3. Lancet. 2000. PMID: 10615881 No abstract available.
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Role of orexins in sleep and arousal mechanisms.Lancet. 2000 Mar 4;355(9206):847. doi: 10.1016/S0140-6736(05)72463-6. Lancet. 2000. PMID: 10711955 No abstract available.
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Increased body-mass index in patients with narcolepsy.Lancet. 2000 Apr 8;355(9211):1274-5. doi: 10.1016/S0140-6736(05)74704-8. Lancet. 2000. PMID: 10770327 No abstract available.
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