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Case Reports
. 2000 Jan;38(1):395-7.
doi: 10.1128/JCM.38.1.395-397.2000.

Microascus cinereus (Anamorph scopulariopsis) brain abscess in a bone marrow transplant recipient

J W Baddley  1 , S A Moser, D A Sutton, P G Pappas
Affiliations
Case Reports

Microascus cinereus (Anamorph scopulariopsis) brain abscess in a bone marrow transplant recipient

J W Baddley et al. J Clin Microbiol. 2000 Jan.

Abstract

We report the first documented case of brain abscess due to the dematiaceous fungus Microascus cinereus, an organism common in soil and stored grain. M. cinereus was isolated from brain abscess material from a bone marrow transplant recipient. The patient responded well to treatment by amphotericin B lipid complex, itraconazole, and a craniotomy but later died from secondary complications caused by graft-versus-host disease.

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Figures

FIG. 1
FIG. 1
Gomori methenamine silver stain of the brain biopsy material.
FIG. 2
FIG. 2
Macroscopic and microscopic features of M. cinereus. (A) Three weeks' growth on PFA (block in center) and cornmeal showing the dematiaceous character and perithecia (pinpoint black dots). (B) Dematiaceous Scopulariopsis species. Magnification, ×920. (C) A perithecium with the ostiole (arrow) borne on a very short neck. Magnification, ×230. (D) Ascospores showing typical convex shape. Magnification, ×920.
See this image and copyright information in PMC

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