Skip to main page content
U.S. flag

An official website of the United States government

Dot gov

The .gov means it’s official.
Federal government websites often end in .gov or .mil. Before sharing sensitive information, make sure you’re on a federal government site.

Https

The site is secure.
The https:// ensures that you are connecting to the official website and that any information you provide is encrypted and transmitted securely.

Access keys NCBI Homepage MyNCBI Homepage Main Content Main Navigation
Review
. 1979 Feb;14(2):181-93.
doi: 10.1007/BF02533870.

The effect of 5,8,11,14-eicosatetraynoic acid on lipid metabolism

L D Tobias, J G Hamilton
Review

The effect of 5,8,11,14-eicosatetraynoic acid on lipid metabolism

L D Tobias et al. Lipids. 1979 Feb.

Abstract

The purpose of this presentation is to review the current state of knowledge regarding 5,8,11,14-eicosatetraynoic acid (ETYA, Ro 3-1428) and its effects on lipid metabolism. Accordingly, the topics discussed include hypocholesterolemic and dermatological studies involving ETYA in both animals and man, as well as the effects of ETYA on desaturase enzymes. Metabolic studies involving ETYA are also noted. Primary interest is focused on the effects of ETYA on selected processes of arachidonate metabolism, and the effect of ETYA on inflammation, platelet aggregation and tumor growth are discussed, keeping in mind the relevance of arachidonate metabolism to these processes.

PubMed Disclaimer

Similar articles

See all similar articles

Cited by

See all "Cited by" articles

References

    1. J Am Chem Soc. 1973 Mar 21;95(6):2054-5 - PubMed
    1. Agents Actions. 1976 Sep;6(5):602-6 - PubMed
    1. Pharmacol Rev. 1974 Mar;26(1):33-67 - PubMed
    1. Xenobiotica. 1972 Sep;2(5):441-5 - PubMed
    1. Biochim Biophys Acta. 1976 Mar 25;428(1):253-6 - PubMed

MeSH terms

LinkOut - more resources