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. 1976 Apr;73(4):1284-7.
doi: 10.1073/pnas.73.4.1284.

Interferon treatment of mice: enhanced expression of histocompatibility antigens on lymphoid cells

P Lindahl, I Gresser, P Leary, M Tovey

Interferon treatment of mice: enhanced expression of histocompatibility antigens on lymphoid cells

P Lindahl et al. Proc Natl Acad Sci U S A. 1976 Apr.

Abstract

Treatment of young and mature mice with potent mouse interferon preparations results in a marked enhancement of the expression of histocompatibility antigens on the surface of thymocytes and splenic lymphocytes as measured by an enhanced absorption of alloantiserum. We postulate that such modifications of the cell surface may reflect an effect of interferon on lymphocyte maturation and may be relevant to the effect of interferon on lymphocyte function.

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