Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri
- PMID: 10637639
- DOI: 10.1016/s0966-842x(99)01646-7
Serotype-converting bacteriophages and O-antigen modification in Shigella flexneri
Abstract
O-antigen modification (serotype conversion) in Shigella flexneri, which is an important virulence determinant, is conferred by temperate bacteriophages. Several serotype-converting phages have been isolated and preliminary characterization has identified the genes involved in O-antigen modification, and has also provided insight into the molecular biology of these phages.
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