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Review
. 2000 Feb;74(4):1593-601.
doi: 10.1128/jvi.74.4.1593-1601.2000.

Signaling activities of gammaherpesvirus membrane proteins

B Damania  1 , J K Choi, J U Jung
Affiliations
Review

Signaling activities of gammaherpesvirus membrane proteins

B Damania et al. J Virol. 2000 Feb.
No abstract available

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Figures

FIG. 1
FIG. 1
Classification of herpesviruses. (A) Phylogenetic tree depicting the three subfamilies of herpesviruses: alpha, beta, and gamma. The phylogram was constructed using the viral DNA polymerase gene by parsimony analysis with the neighbor-joining method. The number of amino acid changes can be determined using the scale shown at the bottom of the tree. (B) Cladogram of the gammaherpesvirus subfamilies. A cladogram of gamma-1 (lymphocryptoviruses) and gamma-2 (rhadinoviruses) herpesviruses was constructed by using the conserved glycoprotein B (gB) gene and a distance analysis. HHV6 and -7, human herpesvirus 6 and 7; MHV68, mouse herpesvirus 68.
FIG. 2
FIG. 2
Schematic representation of the LMP1, STP, K1, and R1 proteins. Interactions with cellular partners and activation of cellular pathways are indicated. Y-P represents the presence of phosphorylated tyrosine residues in K1 and R1.
FIG. 3
FIG. 3
Schematic representation of the LMP2a, Tip, and K15 proteins. Interactions with cellular partners and activation of cellular pathways are indicated. Y-P represents the presence of phosphorylated tyrosine residues in these proteins. Blue-colored T-bar, blocking of signal transduction.
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References

    1. Ablashi D V, Levine P H, Papas T, Pearson G R, Kottaridis S D. First international symposium on Epstein-Barr virus and associated malignant diseases. Cancer Res. 1985;45:3981–3984. - PubMed
    1. Ablashi D V, Schirm S, Fleckenstein B, Faggioni A, Dahlberg J, Rabin H, Loeb W, Armstrong G, Peng J W, Aulahk G, et al. Herpesvirus saimiri-induced lymphoblastoid rabbit cell line: growth characteristics, virus persistence, and oncogenic properties. J Virol. 1985;55:623–633. - PMC - PubMed
    1. Albrecht J C, Fleckenstein B. New member of the multigene family of complement control proteins in herpesvirus saimiri. J Virol. 1992;66:3937–3940. - PMC - PubMed
    1. Albrecht J C, Nicholas J, Cameron K R, Newman C, Fleckenstein B, Honess R W. Herpesvirus saimiri has a gene specifying a homologue of the cellular membrane glycoprotein CD59. Virology. 1992;190:527–530. - PubMed
    1. Alexander, L., L. Denekamp, A. Knapp, M. Auerbach, S. Czajak, B. Damania, and R. C. Desrosiers. The primary sequence of rhesus rhadinovirus isolate 26-95: sequence similarities to Kaposi's sarcoma-associated herpesvirus and rhesus monkey rhadinovirus isolate 17577. J. Virol., in press. - PMC - PubMed

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