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Review
. 2000 Feb;74(4):1593-601.
doi: 10.1128/jvi.74.4.1593-1601.2000.

Signaling activities of gammaherpesvirus membrane proteins

B Damania  1 , J K Choi, J U Jung
Affiliations
Review

Signaling activities of gammaherpesvirus membrane proteins

B Damania et al. J Virol. 2000 Feb.
No abstract available

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Figures

FIG. 1
FIG. 1
Classification of herpesviruses. (A) Phylogenetic tree depicting the three subfamilies of herpesviruses: alpha, beta, and gamma. The phylogram was constructed using the viral DNA polymerase gene by parsimony analysis with the neighbor-joining method. The number of amino acid changes can be determined using the scale shown at the bottom of the tree. (B) Cladogram of the gammaherpesvirus subfamilies. A cladogram of gamma-1 (lymphocryptoviruses) and gamma-2 (rhadinoviruses) herpesviruses was constructed by using the conserved glycoprotein B (gB) gene and a distance analysis. HHV6 and -7, human herpesvirus 6 and 7; MHV68, mouse herpesvirus 68.
FIG. 2
FIG. 2
Schematic representation of the LMP1, STP, K1, and R1 proteins. Interactions with cellular partners and activation of cellular pathways are indicated. Y-P represents the presence of phosphorylated tyrosine residues in K1 and R1.
FIG. 3
FIG. 3
Schematic representation of the LMP2a, Tip, and K15 proteins. Interactions with cellular partners and activation of cellular pathways are indicated. Y-P represents the presence of phosphorylated tyrosine residues in these proteins. Blue-colored T-bar, blocking of signal transduction.
See this image and copyright information in PMC

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