Still a puzzle: why is haem covalently attached in c-type cytochromes?
- PMID: 10647174
- DOI: 10.1016/s0969-2126(00)88334-3
Still a puzzle: why is haem covalently attached in c-type cytochromes?
Abstract
c-Type cytochromes are a group of proteins with diverse structures and functions. Their common feature is covalent attachment of haem to one or more CXXCH motifs. There does not seem to be a single advantageous reason for this covalent attachment.
Similar articles
-
C-type cytochromes: diverse structures and biogenesis systems pose evolutionary problems.Philos Trans R Soc Lond B Biol Sci. 2003 Jan 29;358(1429):255-66. doi: 10.1098/rstb.2002.1192. Philos Trans R Soc Lond B Biol Sci. 2003. PMID: 12594933 Free PMC article. Review.
-
Probing why trypanosomes assemble atypical cytochrome c with an AxxCH haem-binding motif instead of CxxCH.Biochem J. 2012 Dec 1;448(2):253-60. doi: 10.1042/BJ20120757. Biochem J. 2012. PMID: 22928879
-
Crystal structure of oxidized Bacillus pasteurii cytochrome c553 at 0.97-A resolution.Biochemistry. 2000 Oct 31;39(43):13115-26. doi: 10.1021/bi000402j. Biochemistry. 2000. PMID: 11052663
-
Involvement of products of the nrfEFG genes in the covalent attachment of haem c to a novel cysteine-lysine motif in the cytochrome c552 nitrite reductase from Escherichia coli.Mol Microbiol. 1998 Apr;28(1):205-16. doi: 10.1046/j.1365-2958.1998.00792.x. Mol Microbiol. 1998. PMID: 9593308
-
Covalent cofactor attachment to proteins: cytochrome c biogenesis.Biochem Soc Trans. 2005 Aug;33(Pt 4):792-5. doi: 10.1042/BST0330792. Biochem Soc Trans. 2005. PMID: 16042600 Review.
Cited by
-
In vitro formation of a c-type cytochrome.Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7872-6. doi: 10.1073/pnas.132259099. Proc Natl Acad Sci U S A. 2002. PMID: 12060734 Free PMC article.
-
Structure-Function Analysis of the Bifunctional CcsBA Heme Exporter and Cytochrome c Synthetase.mBio. 2018 Dec 18;9(6):e02134-18. doi: 10.1128/mBio.02134-18. mBio. 2018. PMID: 30563894 Free PMC article.
-
Efficient spore synthesis in Bacillus subtilis depends on the CcdA protein.J Bacteriol. 2000 May;182(10):2845-54. doi: 10.1128/JB.182.10.2845-2854.2000. J Bacteriol. 2000. PMID: 10781554 Free PMC article.
-
Examination of abiotic cofactor assembly in photosynthetic biomimetics: site-specific stereoselectivity in the conjugation of a ruthenium(II) tris(bipyridine) photosensitizer to a multi-heme protein.Photosynth Res. 2020 Feb;143(2):99-113. doi: 10.1007/s11120-019-00697-8. Epub 2020 Jan 10. Photosynth Res. 2020. PMID: 31925630 Free PMC article.
-
The Evolution of the Cytochrome c6 Family of Photosynthetic Electron Transfer Proteins.Genome Biol Evol. 2021 Aug 3;13(8):evab146. doi: 10.1093/gbe/evab146. Genome Biol Evol. 2021. PMID: 34165554 Free PMC article.
Publication types
MeSH terms
Substances
LinkOut - more resources
Full Text Sources