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Clinical Trial
. 2000 Feb;163(2):496-8.

A prospective study of the natural history of hematuria associated with benign prostatic hyperplasia and the effect of finasteride

S J Foley  1 , L Z Soloman, A W Wedderburn, K M Kashif, D Summerton, V Basketter, S A Holmes
Affiliations
  • PMID: 10647664
Clinical Trial

A prospective study of the natural history of hematuria associated with benign prostatic hyperplasia and the effect of finasteride

S J Foley et al. J Urol. 2000 Feb.

Abstract

Purpose: We prospectively studied the effect of finasteride on chronic hematuria associated with benign prostatic hyperplasia.

Materials and methods: We prospectively evaluated 57 patients with chronic intermittent hematuria who were randomized to a finasteride treated or a control arm.

Results: In the untreated control group hematuria recurred in 17 patients (63%) within a year but in only 4 (14%) in the finasteride group, which was a statistically significant difference (p <0.05). Surgery was required for bleeding in 7 controls (26%), while no patient on finasteride required surgery.

Conclusions: Hematuria secondary to prostatic bleeding may be significant if not treated. Finasteride appears to be effective for suppressing hematuria caused by benign prostatic hyperplasia and should be considered as treatment.

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