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Editorial
. 2000 Feb;83(2):127-30.
doi: 10.1136/heart.83.2.127.

Homocysteine, B vitamins, and risk of cardiovascular disease

K Robinson
Editorial

Homocysteine, B vitamins, and risk of cardiovascular disease

K Robinson. Heart. 2000 Feb.
No abstract available

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Figures

Figure 1
Figure 1
Pathways for the metabolism of homocysteine. Normal transsulfuration requires cystathionine β synthase with vitamin B6 as cofactor. Remethylation requires 5, 10-methylenetetrahydrofolate reductase and methionine synthase. The latter requires folate as cosubstrate and vitamin B12 (cobalamin) as cofactor. An alternative remethylation pathway also exists using the cobalamin independent betaine-homocysteine methyltransferase.
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