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Review
. 2000 Jan 24;148(2):227-32.
doi: 10.1083/jcb.148.2.227.

The elusive functions of proteoglycans: in vivo veritas

A D Lander  1 , S B Selleck
Affiliations
Review

The elusive functions of proteoglycans: in vivo veritas

A D Lander et al. J Cell Biol. .
No abstract available

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Figures

Figure 1
Figure 1
Pathways in heparan sulfate proteoglycan biosynthesis. HSPGs are produced by the polymerization of polysaccharide chains onto serine residues of core proteins, followed by incomplete carbohydrate modifications involving sulfation, deacetylation, and/or epimerization of glucoronic acid residues to iduronic acid. Additional enzymatic and transport steps are required to generate the UDP sugars and PAPS (3′-phosphoadenosine-5′-phosphosulfate) that participate in many of these reactions (for review see Lindahl et al. 1998).
See this image and copyright information in PMC

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