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Case Reports
. 2000 Jan;129(1):94-6.
doi: 10.1016/s0002-9394(99)00275-5.

Combined intraepithelial squamous neoplasia and atypical fibroxanthoma of the cornea and limbus

N E Engelbrecht  1 , J G Ford, W L White, R P Yeatts
Affiliations
Case Reports

Combined intraepithelial squamous neoplasia and atypical fibroxanthoma of the cornea and limbus

N E Engelbrecht et al. Am J Ophthalmol. 2000 Jan.

Abstract

Purpose: To investigate a case of an unusual neoplasm of the cornea and limbus.

Methods: A 59-year-old man presented with a highly vascularized, nodular mass involving the left cornea and limbus. An excisional biopsy and, subsequently, a superficial lamellar keratectomy and multiple conjunctival biopsies were performed. At the 6-month follow-up examination, repeat conjunctival biopsies were performed.

Results: Histopathologic examination of the corneal specimen showed a high-grade intraepithelial squamous neoplasia (in situ carcinoma) overlying an atypical fibroxanthoma.

Conclusion: We report the clinical and histologic appearance of a corneal/limbal neoplasm consisting of an intraepithelial squamous neoplasia and an atypical fibroxanthoma.

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