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. 1999 Dec;62(12):1678-81.
doi: 10.1021/np990190v.

Oceanapiside, an antifungal bis-alpha,omega-amino alcohol glycoside from the marine sponge Oceanapia phillipensis

G M Nicholas  1 , T W Hong, T F Molinski, M L Lerch, M T Cancilla, C B Lebrilla
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Oceanapiside, an antifungal bis-alpha,omega-amino alcohol glycoside from the marine sponge Oceanapia phillipensis

G M Nicholas et al. J Nat Prod. 1999 Dec.

Abstract

The structure of oceanapiside, an antifungal alpha, omega-bis-aminohydroxylipid glycoside from the temperate marine sponge Oceanapia sp., was elucidated by a combination of 2D NMR, chemical degradation/correlation, and MALDI MS-MS spectrometry. Oceanapiside exhibits antifungal activity against Candida glabrata at 10 micrograms/mL (MIC).

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