A bird's eye view of global methylation
- PMID: 10655046
- DOI: 10.1038/72730
A bird's eye view of global methylation
Abstract
Restriction landmark genomic scanning applied to a broad variety of cancer types can disclose tumour-specific and tumour-type-specific global methylation profiles. This and other genome-scanning approaches allows the rapid analysis of methylation profiles of thousands of genes in parallel-and promises to identify new genes critical to carcinogenesis and other biological processes.
Comment on
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Aberrant CpG-island methylation has non-random and tumour-type-specific patterns.Nat Genet. 2000 Feb;24(2):132-8. doi: 10.1038/72785. Nat Genet. 2000. PMID: 10655057
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