Reliability of the MB/BacT system for testing susceptibility of Mycobacterium tuberculosis complex isolates to antituberculous drugs
- PMID: 10655403
- PMCID: PMC86230
- DOI: 10.1128/JCM.38.2.872-873.2000
Reliability of the MB/BacT system for testing susceptibility of Mycobacterium tuberculosis complex isolates to antituberculous drugs
Abstract
The susceptibility of 115 Mycobacterium tuberculosis complex clinical isolates to isoniazid, streptomycin, ethambutol, and rifampin was assessed by the MB/BacT and BACTEC 460TB systems. The correlation between the two tests was 98.3% for isoniazid, 100% for streptomycin and rifampin, and 95.8% for ethambutol. Turnaround times for antimicrobial susceptibility testing ranged from 5 to 11 days (median, 8.5 days) for MB/BacT and from 4 to 8 days (median, 6 days) for BACTEC 460TB.
References
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- Beer J, Köchler R, Rodloff A C. Investigations about the possibility for testing the susceptibility of mycobacteria with the MB/BacT culture system. Lab Med. 1997;21:390–398.
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