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. 2000 Feb 4;287(5454):845-8.
doi: 10.1126/science.287.5454.845.

Cross-species interactions between malaria parasites in humans

M C Bruce  1 , C A Donnelly, M P Alpers, M R Galinski, J W Barnwell, D Walliker, K P Day
Affiliations

Cross-species interactions between malaria parasites in humans

M C Bruce et al. Science. .

Abstract

The dynamics of multiple Plasmodium infections in asymptomatic children living under intense malaria transmission pressure provide evidence for a density-dependent regulation that transcends species as well as genotype. This regulation, in combination with species- and genotype-specific immune responses, results in nonindependent, sequential episodes of infection with each species.

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