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. 1999 Dec;28(6):1102-9.
doi: 10.1093/ije/28.6.1102.

Adult nutrient intake as a risk factor for Parkinson's disease

C C Johnson  1 , J M Gorell, B A Rybicki, K Sanders, E L Peterson
Affiliations

Adult nutrient intake as a risk factor for Parkinson's disease

C C Johnson et al. Int J Epidemiol. 1999 Dec.

Abstract

Background: This population-based case-control study evaluated nutrient intake as a risk factor for Parkinson's disease (PD) among people aged > or =50 years in metropolitan Detroit.

Methods: Cases (n = 126) were diagnosed between 1991 and 1995 and neurologist-confirmed. Controls (n = 432) were frequency-matched for sex, age (+/-5 years) and race. Using a standardized food frequency questionnaire, subjects reported the foods they ate within the past year.

Results: Estimating the association between PD and risk of being in the highest versus the lowest intake quartile, there were elevated odds ratios for total fat (OR 1.94, 95% confidence interval [CI] : 1.05-3.58), cholesterol (OR 2.11, 95% CI: 1.14-3.90), lutein (OR 2.52, 95% CI: 1.32-4.84) and iron (OR 1.88, 95% CI: 1.05-3.38).

Conclusions: These results suggest an association of PD with high intake of total fat, saturated fats, cholesterol, lutein and iron.

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