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Case Reports
. 1999 Dec;9(6):409-12.
doi: 10.1055/s-2008-1072294.

Lung cancer in a child with a substantial family history of cancer

T Tajiri  1 , S Suita, K Shono, M Kubota, T Taguchi, K Yamanouchi, S Noguchi, M Tsuneyoshi
Affiliations
Case Reports

Lung cancer in a child with a substantial family history of cancer

T Tajiri et al. Eur J Pediatr Surg. 1999 Dec.

Abstract

The occurrence of primary lung cancer is rare in childhood. The case of an 11-year-old boy with primary lung cancer is presented in this report. He had a substantial family history of cancer. His chief complaint was coughing with right chest pain. A chest radiograph showed a coin lesion in the right lower lung. A right lower lobectomy revealed a squamous cell carcinoma (stage IIIA at Japanese TNM classification). Systemic chemotherapy using cisplatin, vindesine, THP-adriamycin and cyclophosphamide was performed. Six months after surgery, a recurrent tumor occurred. An analysis of the familial cancer related genes (p53 gene and mismatch repair gene) showed no abnormality.

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