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Review
. 2000 Jan 27;10(2):R84-7.
doi: 10.1016/s0960-9822(00)00287-6.

RING for destruction?

Affiliations
Free article
Review

RING for destruction?

P S Freemont. Curr Biol. .
Free article

Abstract

Ubiquitination targets proteins for degradation and is a potent regulator of cellular protein function. Recent results implicate the RING finger domain in specific ubiquitination events; it is possible that all RING proteins act as E3 ubiquitin protein ligases, with implications for a variety of biological areas.

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