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. 1976 Aug;73(8):2767-9.
doi: 10.1073/pnas.73.8.2767.

Inhibition of erythrocyte phosphate transport by high pressures

R B Murphy, W F Libby

Inhibition of erythrocyte phosphate transport by high pressures

R B Murphy et al. Proc Natl Acad Sci U S A. 1976 Aug.

Abstract

Pressures of 200-1000 atmospheres (20-100 MPa) are found to decrease significantly the amount of phosphate (H32PO4-2)transported into the rabbit erythrocyte under otherwise physiological conditions. Such compression does not cause irreversible morphological changes or result in membrane disruption. The findings are interpreted in terms of a lipid phase transition induced by the high pressure, which is propagated to the associated phosphate transport system by a physical mechanism.

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References

    1. J Biochem. 1965 Feb;57:116-24 - PubMed
    1. Anal Biochem. 1965 Apr;11:81-7 - PubMed
    1. Biochim Biophys Acta. 1960 Oct 21;44:117-30 - PubMed
    1. Nat New Biol. 1972 Nov 1;240(96):26-8 - PubMed
    1. Biochim Biophys Acta. 1974 Nov 27;373(1):141-4 - PubMed

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